A hormone-free pill, called YCT-529, that temporarily stops sperm production by blocking a vitamin A metabolite has just concluded its first safety trial in humans, getting a step closer to increasing male contraceptive options

  • turdas@suppo.fiEnglish
    5·
    3 months ago

    Going several months with blocked vitamin A metabolism sounds like it’d lead to a vitamin deficiency of some kind.

    • DrWorm@piefed.blahaj.zoneEnglish
      9·
      3 months ago

      The daily pill, called YCT-529, blocks a vitamin A metabolite from binding to its receptor in the testes; this action prevents the chain of gene-expression changes that are required to start the sperm-making process.

      It’s not supposed to effect the rest of the body, but I assume that’s one the side effects they’d be on the lookout for in this trial